Publications

Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

eLife 2026

Shivam R. Shukla, Jessica A. Cross, Monika Kish, Satish K. N. Yadav, Johannes F. Weijman, Laura O’Regan, Judith Mantell, Ufuk Borucu, Xiyue Leng, Chrisinae Schaffitzel, Jonathan J. Philips, Derek N. Woolfson &   Mark P. Dodding 

Controlling cell architecture with protein design

Current Opinion in Cell Biology 2025

Jessica A. Cross, Derek N. Woolfson & Mark P. Dodding 

A de novo designed coiled coil-based switch regulates the microtubule motor kinesin-1

Nature Chemical Biology 2024

Jessica A. Cross, William M. Dawson, Shivam R. Shukla, Johannes F. Weijman, Judith Mantell, Mark P. Dodding & Derek N. Woolfson 

Differential sensing with arrays of de novo designed peptide assemblies

Nature Communications 2023

William M. Dawson, Kathryn L. Shelley, Jordan M. Fletcher, D. Arne Scott, Lucia Lombardi, Guto G. Rhys, Tania J. LaGambina, Ulrike Obst, Antony J. Burton, Jessica A. Cross, George Davies, Freddie J. O. Martin, Francis J. Wiseman, R. Leo Brady, David Tew, Christopher W. Wood & Derek N. Woolfson 

Molecular architecture of the autoinhibited kinesin-1 lambda particle

Science Advances 2022

Johannes F. Weijman, Sathish K. N. Yadav , Katherine J. Surridge, Jessica A. Cross, Ufuk Borucu , Judith Mantell , Derek N. Woolfson , Christiane Schaffitzel, and Mark P. Dodding 

De novo designed peptides for cellular delivery and subcellular localisation

Nature Chemical Biology 2022

Guto G. Rhys, Jessica A. Cross, William M. Dawson, Harry F. Thompson, Sooruban Shanmugaratnam, Nigel J. Savery, Mark P. Dodding, Birte Höcker & Derek N. Woolfson 

Molecular mechanism for kinesin-1 direct membrane recognition

Science Advances 2021

Zuriñe Antón, Johannes F. Weijman , Christopher Williams, Edmund R. R. Moody , Judith Mantell , Yan Y. Yip, Jessica A. Cross, Tom A. Williams , Roberto A. Steiner , Matthew P. Crump , Derek N. Woolfson , and Mark P. Dodding

Kinesin-1 captures RNA cargo in its adaptable coils

Genes & Development 2021

Jessica A Cross, Derek N Woolfson and Mark P Dodding

Fragment-linking peptide design yields a high-affinity ligand for microtubule-based transport

Cell Chemical Biology 2021

Jessica A. Cross, Magda S. Chegkazi, Roberto A. Steiner, Derek N. Woolfson, Mark P. Dodding

Motor–cargo adaptors at the organelle–cytoskeleton interface

Current Opinion in Cell Biology 2019

Jessica A Cross and Mark P Dodding