Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch
bioRxiv 2025
Shivam R. Shukla, Jessica A. Cross, Monika Kish, Satish K. N. Yadav, Johannes F. Weijman, Laura O’Regan, Judith Mantell, Ufuk Borucu, Xiyue Leng, Chrisinae Schaffitzel, Jonathan J. Philips, Derek N. Woolfson & Mark P. Dodding
Controlling cell architecture with protein design
Current Opinion in Cell Biology 2025
Jessica A. Cross, Derek N. Woolfson & Mark P. Dodding
A de novo designed coiled coil-based switch regulates the microtubule motor kinesin-1
Jessica A. Cross, William M. Dawson, Shivam R. Shukla, Johannes F. Weijman, Judith Mantell, Mark P. Dodding & Derek N. Woolfson
Differential sensing with arrays of de novo designed peptide assemblies
William M. Dawson, Kathryn L. Shelley, Jordan M. Fletcher, D. Arne Scott, Lucia Lombardi, Guto G. Rhys, Tania J. LaGambina, Ulrike Obst, Antony J. Burton, Jessica A. Cross, George Davies, Freddie J. O. Martin, Francis J. Wiseman, R. Leo Brady, David Tew, Christopher W. Wood & Derek N. Woolfson
Molecular architecture of the autoinhibited kinesin-1 lambda particle
Johannes F. Weijman, Sathish K. N. Yadav , Katherine J. Surridge, Jessica A. Cross, Ufuk Borucu , Judith Mantell , Derek N. Woolfson , Christiane Schaffitzel, and Mark P. Dodding
De novo designed peptides for cellular delivery and subcellular localisation
Guto G. Rhys, Jessica A. Cross, William M. Dawson, Harry F. Thompson, Sooruban Shanmugaratnam, Nigel J. Savery, Mark P. Dodding, Birte Höcker & Derek N. Woolfson
Molecular mechanism for kinesin-1 direct membrane recognition
Zuriñe Antón, Johannes F. Weijman , Christopher Williams, Edmund R. R. Moody , Judith Mantell , Yan Y. Yip, Jessica A. Cross, Tom A. Williams , Roberto A. Steiner , Matthew P. Crump , Derek N. Woolfson , and Mark P. Dodding
Kinesin-1 captures RNA cargo in its adaptable coils
Jessica A Cross, Derek N Woolfson and Mark P Dodding
Fragment-linking peptide design yields a high-affinity ligand for microtubule-based transport
Jessica A. Cross, Magda S. Chegkazi, Roberto A. Steiner, Derek N. Woolfson, Mark P. Dodding
Motor–cargo adaptors at the organelle–cytoskeleton interface
Current Opinion in Cell Biology 2019
Jessica A Cross and Mark P Dodding
Jess Cross Lab 